David Miller, Director of ADMET Cheminformatics will host a webinar on Wednesday, April 8th to introduce how the ADMET Predictor® HTPK Simulation module can effectively be used to provide early PK assessment in discovery programs. Panelist Eric Jamois will show how these next-generation models can enable realistic PK assessments for chemists and other discovery scientists.
The following topics will be covered:
· Historical insight into modeling human intestinal absorption (HIA)
· Introduction to the Advanced Compartmental Absorption and Transit (ACAT™) model
· Access to high-throughput calculations for fraction absorbed, bioavailability, Cp time curves, AUC and dose optimization.
· Dose dependent considerations for HIA and bioavailability
· Effect of solubility and metabolism on bioavailability and other parameters
· HTPK Simulation module enhancements in APX