How to Understand Aqueous Ionization and Its Influence on Key Physical Properties of Drugs

Authors: Fraczkiewicz R
Conference: DDC
Keywords: aqueous ionization, aqueous solubility, drug development, drug discovery, pH dependent solubility
Software: ADMET Predictor®
Division: Simulations Plus

Part I
“You Must Unlearn What You Have Learned”:
Clearing Up Myths About Aqueous Ionization of Drugs

Part II
“It’s either salty, or it’s free”:
Understanding the pH Dependence of Aqueous Solubility

Part II
“It’s either salty, or it’s free”:
Understanding the pH Dependence of Aqueous Solubility