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Apr 4, 2018
  |  Presentation

Mechanistic Absorption/PBPK Modeling to Predict Positive/Negative Food Effects: Approaches and Special Considerations


  • Early examples and proposed approach
  • Fasted vs. fed state model descriptions – where are we today?
  • Case study: positive food effect predictions – input review
  • Case study: negative food effect predictions – in vitro considerations
  • Future directions and conclusions

Le Club Phase 1 PBPK Symposium 2018, April 4th, 2018, Paris, France

By John DiBella

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