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Mar 3, 2021
  |  Video

Model-Based Meta-Analysis of Anti-tuberculosis Regimen Efficacy in Relapsing Mouse Model Studies

Tuberculosis remains a global health challenge

Although temporarily eclipsed by the COVID-19 pandemic, tuberculosis (TB) remains the leading infectious disease-related cause of death in the world

Drugs are effective but regimens are difficult

  • Long duration
  • Lack of “forgiveness” to poor adherence
  • High comorbidity with HIV

> drug interactions and high bill burden

A regimen that is simpler, shorter in duration, safer, as well as highly effective in both drug susceptible and resistant strains, is required to bring TB under control as an endemic disease.

By Alexander Berg

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Presented at SLP MIDD+ Virtual Conference March 3-4, 2021

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