- The applicability of PBK modelling in next generation risk assessment ( hinges on accurate prediction of human plasma concentrations without reliance on animal in vivo kinetics data.
- IS/IVIVE approach illuminates the influence of various input strategies on PBK model prediction accuracy
- Use the approach to estimate daily dose fold errors of these chemicals in humans
By Priyata Kalra, Haiying Zhou, Michael Lawless
57th Congress of the European Societies of Toxicology, September 10 – 13, 2023, Ljubljana, Slovenia.