Pregnancy PBPK modeling, a necessary step towards safety and efficacy

Authors: Le Merdy M
Conference: SLP MIDD+
Keywords: Cefuroxim, exposure predictions, metronidazole, PBPK model, Phase III, pregnancy, SLP MIDD+ Virtual Conference, SLP2021MIDD
Division: Simulations Plus

Maxime LeMerdy, Senior Scientist discusses clinical trial and post-marketing information along with two case studies for Cefuroxime and Metronidazole.

Topics covered:

  • Ethics and safety concerns
  • Maternal and fetal PK/exposure predictions
  • Postpartum data
  • and more!

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Presented at SLP MIDD+ Virtual Conference March 3-4, 2021