Sarcomatoid Renal Cell Carcinoma: The Apple Doesn’t Fall Far from the Tree

Publication: Clin Cancer Res


The most comprehensive sequencing effort of sarcomatoid renal cell carcinoma (sRCC) to date reinforces the notion that the sarcomatoid component is closely related to the epithelial component of the cancer. This work also challenges the notion that sRCC evolves from low-grade RCC and identifies potential mediators of sarcomatoid differentiation.

By Paulo Bergerot, Neeraj Agarwal, Sumanta K Pal & Jeremy Jones