Phase II dosing regimen
Dosing of 30 mg/kg Q4W could guarantee >90% inhibition of membrane-bound receptor for 9 in 10 individuals
- weight distribution is different?
- patients have reduced clearance due to the renal impairment?
- we start with a loading dose?
Go faster and win with Simulx
By Monika Twarogowska
Presented at SLP MIDD+ Virtual Conference March 3-4, 2021