In Vitro Evaluation of Absorption Characteristics of Peramivir for Oral Delivery

Publication: Eur J Drug Metab Pharmacokinet

Background & Objective

Peramivir is a novel antiviral agent approved for the treatment of severe influenza. However, the development of oral formulation of peramivir has been severely hurdled by poor bioavailability (human, ≤3%). The present work aims to evaluate oral permeability characteristics of peramivir.