What does it take to develop a PBPK model that mimics in vivo behavior of LAIs? Part II

Authors: Lukacova V
Conference: LAI Conference
Software: GastroPlus®
Division: PBPK

Outline

This presentation will take a closer look at possible mechanisms affecting behavior of suspensions of low solubility drugs

  • PBPK model description
  • Effect of dissolution rate Example Cabotegravir
  • Effect of changing depot volume Example Paliperidone Palmitate

By Viera Lukacova