A Charles River Laboratories company, have teamed up to create a winning combination!
SOLVO provides high quality data from their world-class laboratories to support DILIsym software representations of bile acid homeostasis and bilirubin processing via the following endpoints:
- BSEP inhibition;
- MRP2, MRP3 and MRP4 inhibition;
- NTCP inhibition;
- OATP1B1 and OATP1B3 inhibition;
- MDR3 inhibition.
Many times, DILIsym results also help with selection of future transporter assays to be completed, making the data collection / simulation cycle iterative.