GastroPlus Version 9.8.3

Version 9.8.3 is now available for download. Please contact us if you need assistance with upgrading or would like to activate a software evaluation.

Request an Evaluation

Meet Our Experts in Person

Upcoming Scientific Conference

Development of a Physiologically Based Pharmacokinetic (PBPK) Model for Pexidartinib to Evaluate the Impact of Meal Contents and Intake Timing on Drug Exposure

• Date: Tuesday, Nov. 1st
• Time: 7:00-9:00 am, 1:00-2:30 pm, 4:00-5:30 pm MDT
• Poster presented by: Shintaro Nakayama, Daiichi (Simulations Plus coauthors: Jim Mullin, Sandra Suarez-Sharp, Viera Lukacova)

A Physiologically Based Pharmacokinetic Model of Long-Acting Lenacapavir

• Date: Tuesday, November 1st
• Time: 7:00-9:00 am, 1:00-2:30 pm, 4:00-5:30 pm MDT
• Poster presented by: Abdul Naveed Shaik, Gilead (Simulations Plus coauthor: Viera Lukacova)

PKUK (Nov. 2-4) Canterbury Cathedral, UK

• Geraldine Ayral, Lixoft VP of Applications will present “A novel model-integrated design for bioequivalence of long-acting injectables” on Thursday, Nov. 3rd, from 4:10 – 4 :50 pm BST

ASN Kidney Week (Nov. 3-6)

• Meet DILISym Services Sr. Principal Scientist, Jeff Woodhead at booth #1432.

AASLD The Liver Meeting (Nov. 4-8)

• Connect with DILISym Services CSO Scott Q. Siler & Scientist II Vinal Lakhani at booth #619.

4th Asian Pharmacometrics Network Symposium (Nov. 9-10)

• Our Monolix team will host a virtual FREE 2-day pre-conference workshop. Register here.

View our Events Calendar

Novice & Advanced Users

Workshops

• Complimentary Introduction to GastroPlus – Training caters to new users, those returning after an extended hiatus, or switching to an updated version. (Nov 7 & Dec. 5)
• 4th Asian Pharmacometrics Network Symposium pre-conference workshops 
  • Development of population pharmacokinetic models with Monolix™ (Nov. 7, 2:30-5:30 pm Malaysia Time)
  • Development of population PKPD models with Monolix and simulation of new scenarios in Simulx™ (Nov. 8, 2:30-5:30 pm Malaysia Time)
• GastroPlus Advanced Workshop: DMPK and Clinical Pharmacology – A more in-depth exploration of PBPK theory, execution, and application of the software. (Nov. 14-17) 
• DILIsym® Introductory Course – A beginner’s course for clinicians, pharmaceutical/biotechnology scientists, and engineers in the areas of toxicology, clinical pharmacology, pharmacovigilance, DMPK, and ADME – prior experience with DILIsym is not required. (Nov.15-16)
• European GastroPlus Introductory Workshop This workshop provides participants with the necessary information and skills to execute basic PBPK modeling and simulations and provide a foundational understanding of the GastroPlus software. (Nov. 21-25)

View All Workshops

NEW Video Series

Get to Know a Scientist

Learn more about our terrific team of modelers and scientists. With diverse backgrounds ranging from big pharma, to regulatory agencies, and more!

• Daniela Silva, Ph.D., Scientist I
• Denise Morris Ph.D., Director, Learning Services
• Jessica Spires, Ph. D, Senior Scientist II
• Maxime Le Merdy, Ph.D., Senior Scientist
• Sandra Suarez-Sharp, Ph.D., Vice President, Regulatory Affairs
• Xavier Pepin, Ph.D., Associate Vice President, Regulatory Affairs

Meet our Team

In Case You Missed It

Recent News

Press Releases:

• Simulations Plus Releases State-of-the-Art QSP Software for Interstitial Lung Disease
• Simulations Plus Enters New Collaboration to Enhance Machine Learning Models for Ionization Constants (pKa)
• Simulations Plus Reports Fourth Quarter and Full Fiscal Year 2022 Financial Results 

Join our Team! Open positions:

• Director, Corporate Marketing
• Internship+
• Jr. PBPK Modeler
• Modeling Applications Scientist
• Pharmacometrician
• QSP/QST Modeling Scientist
• QT/C++ Programmer
• Sr. PBPK Modeler

Career Center

Copyright © 2022 Simulations Plus, All rights reserved.

Simulations Plus, Inc. Corporate Headquarters
42505 10th Street West
Lancaster, CA 93534
Telephone: +1-661-723-7723

Cognigen, a Simulations Plus division

500 Seneca Street, Suite 600
Buffalo, NY 14204
Telephone: +1-716-633-3463

DILIsym Services, a Simulations Plus division
Six Davis Drive
PO Box 12317
Research Triangle Park, NC 27709
Telephone: +1-919-558-1323

Lixoft, a Simulations Plus division
8 rue de la Renaissance Batiment D
92160 Antony, France
Telephone: +33 9 72 53 91 80