Senior Principal Scientist
Physiologically Based Pharmacokinetics (PBPK) Solutions
James Mullin is a Senior Principal Scientist in the Simulations Technologies group and Product Manager of DDDPlus™ and MembranePlus™, two in silico software tools to predict in vitro dissolution and permeability & clearance mechanisms/kinetics. James has 17 years of experience in computational modeling in the pharmaceutical industry, spending 10 years at Bend Research before joining Simulations Plus in 2014.
In his most recent research, James developed models for the effect of meal type and calories in the fed state, dynamic fluid volume in the intestine, pulmonary absorption of volatile materials, intra-articular delivery, and enhancements to the population simulator based on an industry collaboration. Additionally, James has implemented models for the Artificial Stomach and Duodenum and Biphasic dissolution experiments in DDDPlus. James has also contributed to several FDA & EMA collaboration grants for Simulations Plus and trains scientists on the use of mechanistic modeling & simulation technology.