Join us at ACoP 2025, the leading annual conference for the global pharmacometrics community. This year’s meeting will feature cutting-edge science, hands-on workshops, and insightful presentations from thought leaders across industry, academia, and regulatory agencies. Whether you’re a seasoned expert or new to the field, ACoP 2025 offers valuable opportunities to learn, network, and contribute to the advancement of model-informed drug development.

Be sure to stop by the Simulations Plus booth #7 and meet with our experts, who will be happy to answer any questions you have. We hope to see you there!

Can’t Miss Presentations!

Title: Thales Workshop
Date/Time: Saturday, October 18th, 8:00 AM – 5:00 PM
Location: Homestead 1
Presenters: 

• Cameron Meaney – Scientist I, Scientific Staff, QSP
• Clifton Anderson – Scientist II, Scientific Staff, QSP
• Christina Battista – Senior Principal Scientist, Mgr, Scientific Staff, QSP
• Ryan Suderman – Director/Senior Principal Scientist, Scientific Staff, QSP

Title: Differentiated MIDD strategies to accelerate clinical development in metabolic diseases are worth their weight
Date/Time: Sunday, October 19th, 11:00 AM – 12:30 PM
Location: Colorado B-D
Co-Chairs:

• Dr. Theodore Rieger, Director, Pharmacometrics, Pfizer
• Dr. Brian J. Schmidt, Executive Director, Clinical Pharmacology, Madrigal Pharmaceuticals

Presenters:

• Dr. Karen Schneck, Advisor, Eli Lilly and Company
• Dr. Rune Overgaard, Senior Scientific Director, Novo Nordisk
• Dr. Scott Siler, Chief Science Officer, Simulations Plus
• Dr. Sibylle Neuhoff, Senior Scientific Advisor, Transporter Group Head, Certara Predictive Technologies

Title: (S-072) Automated concentration-QT data preparation, model selection and reporting in R
Date/Time: Sunday, October 19th, 7:00 AM – 5:00 PM MDT
Location: Colorado A
Presenters: 

• Jonathan Chauvin – Co-Chief, Product & Technology Officer, Product Managment, Shared Services 

Title: (S-057) mlxDesignEval: A novel R package for design evaluation based on MonolixSuite, and its comparison to popED and PFIM
Date/Time: Sunday, October 19th, 7:00 AM – 5:00 PM MDT
Location: Colorado A
Presenters: 

• Monika Twarogowska – Sr. Principal Scientific Product Specialist, Product Enablement, Pharmacometrics & Clinical Pharmacology

Title: Differentiated MIDD strategies to accelerate clinical development in metabolic diseases are worth their weight (11:00 AM – 12:30 PM)
Date/Time: Sunday, October 19th, 11:00 AM – 12:30 PM
Location: Colorado B-D
Presenters: 

• Scott Q. Siler – Chief Science Officer, Scientific Staff, QSP

Title: Translation of weight loss and prediction of liver pharmacodynamics in NASH across a range of mechanism quantitative systems pharmacology modeling.
Date/Time: Sunday, October 19th, 11:45 AM – 12:07 PM
Location: Colorado B-D
Presenters: 

• Scott Q. Siler – Chief Science Officer, Scientific Staff, QSP

Title:(M-100) Development of a Quantitative Systems Toxicology Model to Predict Drug-Induced Liver Injury in Pediatrics
Date/Time: Monday, October 20, 2025, 7:00 AM – 5:00 PM MDT
Location: Colorado A
Presenters:

• Scott Q. Siler – Chief Science Officer, Scientific Staff, QSP

Title: (M-015) Hybrid MBMA-QSP Model Predicts T-Cell Engager Plus Cereblon E3 Ligase Modulatory Drugs Combination Outcomes As A Function Of Prior Therapies In Relapsed/refractory Multiple Myeloma
Date/Time: Monday, October 20th, 7:00 AM – 5:00 PM
Location: Colorado A
Presenter: 

• Clifton Anderson – Scientist II, Scientific Staff, QSP

Title: (M-014) Multiple myeloma QSP model enables evaluation of iberdomide dosing schedules post-ASCT in NDMM patients for the EXCALIBER Maintenance study
Date/Time: Monday, October 20th, 7:00 AM – 5:00 PM
Location: Colorado A
Presenter: 

• Clifton Anderson – Scientist II, Scientific Staff, QSP

Title: (M-103) Population Pharmacokinetic Analysis of QRL-201 in Plasma and CSF in Patients With Amyotrophic Lateral Sclerosis From A First-in-Human Phase 1 Multiple Ascending Dose Escalation Study
Date/Time: Monday, October 20th, 7:00 AM – 5:00 PM
Location: Colorado A
Presenter: 

• Gaurav, Mitali – Assistant Director, Pharmacometrics, Scientific Staff, Pharmacometrics & Clinical Pharmacology
  

Title: Enabling Earlier Predictions of Hepatotoxic Risk with Quantitative Structure-Activity Relationship-Machine Learning (QSAR-ML) and Quantitative Systems Toxicology (QST) Models
Date/Time: Tuesday, October 21st, 7:00 AM – 9:00 AM
Location: Colorado A
Presenter:

• Christina Battista – Senior Principal Scientist, Mgr, Scientific Staff, QSP

Title: Scaling Peaks Unclimbed: How QSP is Shaping the Future Landscape of MIDD in Diseases Beyond Oncology
Date/Time: Tuesday, October 21st, 9:00 AM
Location: Willow Lake 3-5
Co-Chair:

• Ryan Suderman – Director/Senior Principal Scientist, Scientific Staff, QSP

Title: Will harmonization in guidance lead to consistency in assessment and regulatory decisions, with a focus on PBPK modeling in new drug approvals (NDAs) and marketing authorization applications (MAAs)?
Date/Time: Tuesday, October 21st, 11:15 – 11:30 AM
Location: Willow Lake 3-5
Presenter: Susie Zhang – Vice President, Regulatory Strategies, Scientific Staff, PBPK

Title: Machine learning algorithms for structural model selection – comparison and implementation
Date/Time: Tuesday, October 21st, 10:45 – 12:15 AM
Location: Red Rock 8-9
Presenter: Frano Mihaljevic – Sr. Scientific Product Specialist, Product Enablement, Pharmacometrics & Clinical Pharmacology

ACoP Pre-Conference Workshop Details

2-DAY WORKSHOP  

Simulations Plus: From PK-PD Models to Simulations: A Hands-On Workshop using MonolixSuite™
Dates/Time: October 17th – 18th, 8:00 AM – 5:00 PM
Presenters:

• Monika Twarogowska – Sr. Principal Scientific Product Specialist, Product Enablement, Pharmacometrics & Clinical Pharmacology
• Frano Mihaljevic – Sr. Scientific Product Specialist, Product Enablement, Pharmacometrics & Clinical Pharmacology

Find more details here.

1-DAY WORKSHOP

Simulations Plus: End-to-end clinical trial modeling with the Thales QSP software platform
Date/time: October 18th, 8:00 AM – 5:00 PM
Presenters:

• Ryan Suderman – Director/Senior Principal Scientist, Scientific Staff, QSP
• Cameron Meaney – Scientist I, Scientific Staff, QSP
• Clifton Anderson – Scientist II, Scientific Staff, QSP

Find more details here.

Simulations Plus Staff in Attendance: 

• Amparo de la Peña, Ph.D. – Vice President, Pharmacometric Services, Scientific Staff, Pharmacometrics & Clinical Pharmacology 
• Arlene Padron – Senior Director, Business Development, Sales, Shared Services
• Cameron Meaney – Scientist I, Scientific Staff, QSP
• Christina Battista – Senior Principal Scientist, Mgr, Scientific Staff, QSP
• Clifton Anderson – Scientist II, Scientific Staff, QSP
• Elizabeth A. Ludwig, Pharm.D. – Associate Vice President, Quantitative Clinical Pharmacology, Clinical Pharmacology & Pharmacometrics Solutions
• Frano Mihaljevic – Sr. Scientific Product Specialist, Product Enablement, Pharmacometrics & Clinical Pharmacology
• Guillaume Bonnefois, Ph.D. – Director, Pharmacometrics, Scientific Staff, Pharmacometrics & Clinical Pharmacology
• Heather Barcomb, M.A. – Assistant Director, Pharmacometrics, Scientific Staff, Pharmacometrics & Clinical Pharmacology
• Heather Squire – Business Development Director, Sales, Shared Services
• Jill Fiedler-Kelly, M.S., F.I.S.oP. – President, Services Solutions, Scientific Staff, Pharmacometrics & Clinical Pharmacology
• Jennifer Johnson, Learning Services Manager, Clinical Operations, Shared Services
• Jonathan Chauvin, Ph.D. – Co-Chief, Product & Technology Officer, Product Managment, Shared Services 
• Julie A. Passarell, M.A. – Associate Vice President, Pharmacometrics, Scientific Staff, Clinical Pharmacology & Pharmacometrics Solutions
• Kelly Fellows Maxwell, Ph.D. – Associate Director, Pharmacometrics, Scientific Staff, Clinical Pharmacology & Pharmacometrics Solutions
• Mitali Gaurav, Pharm.D. – Assistant Director, Pharmacometrics, Scientific Staff, Clinical Pharmacology & Pharmacometrics Solutions
• Monika Twarogowska, Ph.D. – Sr. Principal Scientific Product Specialist, Product Enablement, Pharmacometrics & Clinical Pharmacology
• Nancy Lin – Pharmacometrician I, Scientific Staff, Pharmacometrics & Clinical Pharmacology
• Olivier Barriere – Senior Director, Pharmacometrics, Scientific Staff, Pharmacometrics & Clinical Pharmacology
• Pauline Traynard, Ph.D. – Director, Scientific Product Enablement, Product Management, Pharmacometrics & Clinical Pharmacology
• Peter Kilford – Associate Vice President, Software Business Development, Sales, Shared Services
• Ryan Suderman – Director/Senior Principal Scientist, Scientific Staff, QSP
• Saumi Rahatekar – Senior Director, Business Development, Sales, Shared Services
• Shawn O’Connor – Chief Executive Officer, Executive Management, Shared Services
• Scott Siler – Chief Science Officer, Scientific Staff, QSP
• Stephanie Kollmann – Associate Product Specialist, Product Enablement, Pharmacometrics & Clinical Pharmacology
• Steve Chang – Global Head of Strategic Alliances, Business Development, Shared Services
• Susie Zhang – Vice President, Regulatory Strategies, Scientific Staff, PBPK
• Suvarchala Avvari – Scientist II, Scientific Staff, PBPK
• Tom Sun – Vice President, Strategic Consulting Services, Scientific Staff, Pharmacometrics & Clinical Pharmacology
• Yawen Fan – Business Development Consultant, Sales, Shared Services