February 2022 GastroPlus Newsletter

Authors: O’Connor D
Software: GastroPlus®
Division: Simulations Plus

MIDD+ 2022 starts tomorrow… please register now! We are fast approaching 1000 registered attendees! There are many subject tracks that will be well worth your time. Registration is FREE & required for entry. The conference is completely online so no travel is required.

For those of you who are using the dermal module in GastroPlus, we will be releasing a new version of MembranePlus™ with:

  • New models of in vitro penetration (IVPT) and release (IVRT) tests for transdermal formulations for novel analysis of absorption and dissolution kinetics
  • Expanded membrane transport model parameters for improved predictions of permeability coefficients for both small and peptide molecules
  • Improved data handling and simulation performance

These new extensions in MembranePlus will fit seamlessly with recent improvements to the GastroPlus transdermal compartmental absorption and transit (TCAT™) platform, giving researchers a unique and innovative simulation engine to predict exposure following topical administration of formulations dosed in animals and humans.

Just let me know if you would like a trial or a call to discuss the platform.

Please take a moment to view the video below from our Executive Director of HR Lindsay Luke inviting you to help us find scientists that might wish to join our team. We have many exciting career opportunities.

John DiBella often asks me… “Isn’t this the best job you have ever had?” I have always answered him, that it is certainly one of the best. If you promise not to tell him…it really is the best job I have ever had!

I get to be part of a great group of smart and dedicated people all focused on bringing the best software and consulting to you, our clients. We are a fun band of professionals who work hard and play hard. We have the privileged position of providing both products and services which help speed up the process of bringing life-saving drugs to market for people in need worldwide.

“Imagining the possible… GastroPlus!” A challenging and exciting environment that I love… just don’t let John know I said it!

Lastly, at any time, if you have questions or wish to add any GastroPlus module on a trial basis we are happy to help. Please let me know how we may assist you and your teams continue to increase both the utility and understanding of GastroPlus.

By Dan O’Connor