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Apr 10, 2017
  |  Poster

Modeling of Active Transport and Metabolism for in vitro Suspended and Sandwich Hepatocyte Assays Utilizing MembranePlus

Overview

• MembranePlus™ – a software platform for simulaton of drug transport in cell assays.
• Development of Hepatocyte Transport Model
– Sandwich and plated hepatocytes.
– Suspended hepatocytes.
• Model Case Studies
– Sodium Taurocholate transport
– Sta1ns (uptake+metabolism)
– IVIVE with combina1on of MembranePlus and GastroPlus

SOLVO Meet the Experts Transporters Conference, April 10-12, 2017, San Francisco, CA

By James Mullin

 

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