Full-scale NAFLDsym consulting projects are customized to each drug development application based on your goals and can include:
  • optimization of clinical trial protocols by determining favorable dosing paradigms and outcome (i.e., liver fat reduction) measurement frequency;
  • evaluation of efficacy and safety potential for targets and/or specific compounds utilizing key laboratory and/or clinical data describing DMPK and pharmacodynamic characteristics;
  • interpretation of preclinical and clinical data to provide improved mechanistic understanding of observed responses to compounds;
  • prioritization of compounds and targets;
  • determination of responsive and non-responsive patient subsets to support clinical trial patient recruitment;
  • predictions of efficacy for novel combinations of treatments;
  • and much more!

NAFLDsym consulting services are available to anyone, whether or not your organization is a member of the DILI-sim Initiative, which is focused on development of the DILIsym software tool for liver safety.

NAFLDsym® services is scientific research and consultation services in the fields of research and development of compounds such as drugs or chemicals for others, including conducting simulations of compounds to evaluate and model their effects on non-alcoholic fatty liver disease (NAFLD).

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About NAFLDsym® Services