01. Discover
DILIsym Services and Cyprotex

An Evotec Company, have teamed up to enhance the quality of your toxicology predictions!

Cyprotex provides high quality in vitro data and expertise to support DILIsym software representations of mitochondrial dysfunction, oxidative stress, and lipotoxicity via the following endpoints:

  • Mitochondrial function assay with the Agilent Seahorse XF Analyzer providing outputs such as oxygen consumption rate (OCR) and extracellular acidification rate (ECAR)
  • Cell health parameters from high content imaging assessments with markers such as oxidative stress or reactive oxygen species (ROS), glutathione (GSH), mitochondrial membrane potential, ATP and steatosis
  • Mass spectrometry services to assess intracellular concentrations for each assay

02. Resources
Peer-reviewed Publications