What is the Optimization Module?
The Optimization Module for GastroPlus® extends and enhances the program’s basic capabilities in several important ways:
- To automatically fit physicochemical, pharmacokinetic, formulation and/or physiology model parameters to data
- To optimize study designs (e.g., dosing regimens) and dose
- To “deconvolute” in vivo release profiles to achieve a target plasma (or tissue) concentration vs. time curves for parent and/or metabolites