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October 2021 GastroPlus Newsletter
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October 2021 GastroPlus Newsletter
  • October 13, 2021
  • Blog

October 2021 GastroPlus Newsletter

Authors: O’Connor D
Keywords: AAPS Pharmasci 360, admet predictor, gastroplus, gastroplus pbpk modeling
Software: GastroPlus®
Division: PBPK

As I mentioned last month, we are finally going to be attending a real conference, in-person, “non-virtually”!  Please stop by and visit us at our booth at AAPS PharmSci 360 on October...

  • Read More
September 2021 GastroPlus Newsletter
  • September 14, 2021
  • Blog

September 2021 GastroPlus Newsletter

Authors: O’Connor D
Keywords: AAPS Pharmasci 360, admet predictor, GP Newsletter, High throughput pharmacokinetics module, HTPK, SLP MIDD+ Virtual Conference
Software: GastroPlus®
Division: PBPK

Hooray!... We are finally going to be attending a real conference, in-person, “non-virtually”!

  • Read More
September 2021 News/Events
  • September 7, 2021
  • Blog

September 2021 News/Events

Keywords: ADMET modeling, monthly newsletter, PBPK modeling, pharmacometrics, SLP MIDD+ Virtual Conference
Software: ADMET Predictor®, DILIsym®, GastroPlus®, IPFsym®, Monolix®, NAFLDsym®, RENAsym®
Division: PBPK, Quantitative Systems Pharmacology (QSP)
  • Read More
August 2021 GastroPlus Newsletter
  • August 10, 2021
  • Blog

August 2021 GastroPlus Newsletter

Authors: O’Connor D
Keywords: AAPS Pharmasci 360, GP Newsletter, Simulations Plus
Software: GastroPlus®
Division: PBPK

Coinciding with the milestone of our “silver anniversary” comes the news of the “passing of the torch”!

  • Read More
August 2021 News/Events
  • August 3, 2021
  • Blog

August 2021 News/Events

Keywords: monthly newsletter, PBPK model, PBPK modeling, PopPK, qsp, QST
Software: DILIsym®, IPFsym®, Monolix®, NAFLDsym®, RENAsym®
Division: Clinical Pharmacology and Pharmacometrics (CPP), PBPK, Quantitative Systems Pharmacology (QSP)
  • Read More
July 2021 GastroPlus Newsletter
  • July 13, 2021
  • Blog

July 2021 GastroPlus Newsletter

Authors: O’Connor D
Keywords: AAPS, AAPS Pharmasci 360, gastroplus, GP Newsletter
Software: ADMET Predictor®, GastroPlus®
Division: PBPK

Thanks to all of you for the many contributions that you all have made over the years to help us reach the significant milestone of our “silver anniversary”.

  • Read More
July 2021 News/Events
  • July 6, 2021
  • Blog

July 2021 News/Events

Keywords: monthly newsletter, pharmacometric modeling
Software: RENAsym®
Division: Clinical Pharmacology and Pharmacometrics (CPP), PBPK, Quantitative Systems Pharmacology (QSP)
  • Read More
New PBPK Modeling & Simulation Courses for Fall 2021
  • June 30, 2021
  • Blog

New PBPK Modeling & Simulation Courses for Fall 2021

Authors: Morris D
Keywords: gastroplus, MIDD (model-informed drug development), PBPK, workshops
Software: GastroPlus®
Division: PBPK

The world is constantly changing, and with the advancement of technology, it is moving at an accelerated pace.

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Quantifying Exposure is the Foundation of Pharmacometric Analysis
  • June 15, 2021
  • Blog

Quantifying Exposure is the Foundation of Pharmacometric Analysis

Authors: Dykstra, K
Keywords: dosing recommendations, exposure-response, noncompartmental analysis (NCA), Pharmacometric analysis, PK analysis, PK/PD, population PK
Division: Clinical Pharmacology and Pharmacometrics (CPP)

Kevin Dykstra answers questions like, "Why do we care about Drug Exposure?"

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Training and Education – Learning tomorrow’s science… today.
  • June 14, 2021
  • Blog

Training and Education – Learning tomorrow’s science… today.

Authors: Fiedler-Kelly J
Keywords: modeling and simulation, pharmacometrics, pop PK model
Division: Clinical Pharmacology and Pharmacometrics (CPP)

As I think back on 20+ years of lecturing on the population modeling & simulation (M&S) approach, I am simultaneously struck by how much has changed and how much has remained the same.

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Ensuring the Quality and Accuracy of Analysis-Ready Datasets
  • June 14, 2021
  • Blog

Ensuring the Quality and Accuracy of Analysis-Ready Datasets

Authors: Hitchcock D
Keywords: blinded study, data assembly, graph library, qa, qc, quality
Division: Clinical Pharmacology and Pharmacometrics (CPP)

Our experience in data assembly is extensive: we’ve been building analysis-ready datasets for pharmacometric modeling and simulation for over 25 years.

  • Read More
June 2021 GastroPlus Newsletter
  • June 8, 2021
  • Blog

June 2021 GastroPlus Newsletter

Authors: O’Connor D
Keywords: 25th anniversary, dddplus, Disso India, gastroplus, GP Newsletter, Simulations Plus
Software: GastroPlus®
Division: PBPK

A long time ago, in a desert far, far away…

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June 2021 News/Events
  • June 1, 2021
  • Blog

June 2021 News/Events

Keywords: COVID-19, in vitro data, monthly newsletter
Software: DDDPlus™, GastroPlus®, IPFsym®, Monolix®
Division: Clinical Pharmacology and Pharmacometrics (CPP), PBPK, Quantitative Systems Pharmacology (QSP)
  • Read More
May 2021 GastroPlus Newsletter
  • May 11, 2021
  • Blog

May 2021 GastroPlus Newsletter

Authors: O’Connor D
Keywords: DILIsym, gastroplus, HTPK
Software: GastroPlus®
Division: PBPK

We hope that you and yours are coming out of our Covid enforced isolation.

  • Read More
Evaluating the Hepatotoxicity of Compound V with QST/QSP Modeling
  • May 10, 2021
  • Blog

Evaluating the Hepatotoxicity of Compound V with QST/QSP Modeling

Authors: Lakhani VV, Nevarez J
Keywords: ALT elevation frequencies, Compound V, hepatotoxicity, PK data, QSP modeling, QST modeling
Software: DILIsym®, GastroPlus®
Division: Quantitative Systems Pharmacology (QSP)

Is your compound causing drug-induced liver injury?

  • Read More
May 2021 News/Events
  • May 5, 2021
  • Blog

May 2021 News/Events

Keywords: HTPK, monthly newsletter, NAFLDsym, PK data
Software: ADMET Predictor®, DILIsym®, NAFLDsym®
Division: Clinical Pharmacology and Pharmacometrics (CPP), PBPK, Quantitative Systems Pharmacology (QSP)

Did you know? We provide high-quality analysis & support services including non-compartmental PK analysis, population PK and PK/PD modeling, PBPK modeling in GastroPlus®, and statistical modeling, focusing on...

  • Read More
  • Click to View
Applications of Pharmacometrics in Phase 1 Studies
  • May 3, 2021
  • Blog

Applications of Pharmacometrics in Phase 1 Studies

Authors: Patel Y
Keywords: dose selection, fih, pharmacometrics, Phase 1
Division: Clinical Pharmacology and Pharmacometrics (CPP)

Phase 1 is a drug development stage where you start the clinical evaluation of the drug.

  • Read More
Meet Saumitra Rahatekar, delivering life science solutions
  • April 30, 2021
  • Blog

Meet Saumitra Rahatekar, delivering life science solutions

Authors: Rahatekar S, Nevarez J
Keywords: analysis of preclinical and clinical trial data, biotechnology, clinical development, Clinical Pharmacology Consulting, data assembly, data programming, life science, MonolixSuite, MonolixSuite Playlist, NONMEM, Pharmacometric analysis, pharmacovigilance, regulatory affairs
Division: Clinical Pharmacology and Pharmacometrics (CPP)
  • Read More
5 Takeaways from “The Impact of Modeling in Drug Development” panel discussion
  • April 15, 2021
  • Blog

5 Takeaways from “The Impact of Modeling in Drug Development” panel discussion

Keywords: MIDD (model-informed drug development), PBPK modeling, physiological based biopharmaceutics models (PBBM)
Division: Cheminformatics, Clinical Pharmacology and Pharmacometrics (CPP), PBPK, Quantitative Systems Pharmacology (QSP), Regulatory Strategies
  • Read More
Using DDDPlus™ to Predict in vivo API Exposure Levels
  • April 15, 2021
  • Blog

Using DDDPlus™ to Predict in vivo API Exposure Levels

Keywords: dddplus, modeling and simulation, PBPK
Software: DDDPlus™
Division: PBPK

There has been an increasing desire to incorporate mechanistic models of in vitro experiments to evaluate the interplay between...

  • Read More
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